Commercial Pest Control Solutions for Knoxville Business Owners

Our team of 18 expert service technicians has over 100 years of combined experience treating medical, retail, commercial, government, hospitality, and industrial properties of all kinds.

We understand the unique challenges involved in a business environment and the confidentiality required. We are certified by the State of Tennessee and trained to properly and safely rid your business of unhealthy and unwanted pests. Our expert technicians have passed criminal background checks, have security clearances for state and federal services, and undergo continuing education and training. We schedule services around your business hours with the least amount of disruption to your business possible.

If you want to make sure pests go away and stay away, we can set up a customized monthly or quarterly service plan. This regular maintenance will build barriers to keep pests out and away from you and your customers.


Commercial Bed Bug Treatment

Bed bug infestations are currently the most problematic pest in the public domain. We combat these unwanted pests with a safe, effective thermal heat process. We use equipment designed to raise the temperature in the area of infestation, penetrating all cracks and crevices where bed bugs hide. This proven process eliminates both bed bugs and their eggs. No potentially harmful gas is used.

Contact us today for a free pest control inspection. Let Otis Termite & Pest Control be your business partner in the fight against pests, so you can focus on your work.



Emily Moeck

"I unknowingly moved into a home that had a HUGE bed bug infestation..."Don't you worry, we are on top of this until they are gone, I promise!"... Jack was knowledgeable and honest in his assessment of my house/treatment methods. Thank you, Jack and Rocky and the whole Otis team! My home is home again!"


Joshua Weaver

"Prompt responses and appointment times. Very friendly and knowledgeable. Straight forward service without any "pushing" for extras."


Charlotte Bishop

"These guys were super helpful and kind. Jack thoroughly explained every procedure and made what could have been a horrible situation much more bearable. I definitely recommend them!"


Tamie Ridenour

"Excellent service and staff!! They were at my house the same day I called, for New construction pre-treatment!"


Cathy Amos

"Highly recommend! Jack and Rocky are great! You've got a business and highest recommendation! Great people to work with!"

Contact the experts

Request a Free Inspection for your Pest Control Needs

Whether you have a residential or a commercial property need, please take advantage of our free inspection, and inquire about any of our pest control services in East Tennessee, please complete this short form and we’ll be in touch soon!

Visit Otis Pest Control

Main Headquarters

112 Hayfield Road
Knoxville, TN 37922

Call Otis Pest Control

Location Specific Phone Numbers

  • Knoxville (serving Knox County)

  • Maryville (serving Blount County)

  • Lenoir City (serving Loudon & Monroe Counties)

  • Oak Ridge (serving Anderson, Roane, Scott, Morgan, Campbell, Union, & Cumberland Counties)

  • Sevierville (serving Sevier, Hamblen, & Cocke County)


Servicing all areas of Knoxville and surrounding counties and the Greater East TN area including Tri-Cities, Johnson City, Crossville & Chattanooga.

Please Submit Area of Interest